How to use antibiotics in hospital
1)Get appropriate microbiological samples before antibiotic administration & carefully interpret the results.
(2)Avoid the utilization of antibiotics to treat fever use them to treat infection & investigate the root cause of fever before starting treatment.
3)Start empirical antibiotic treatment after taking cultures,tailoring it to the site of infection ,risk factors for multidrug resistant bacterium, & the local microbiology and susceptibility patterns.
4)Prescribe drugs at the optimal dosing and for an approximate duration, adapted to each clinical situation and patient characteristics.
5)Use antibiotic combinations only where the current evidence suggests some benefits.
6)When possible avoid antibiotics with a higher likelihood of promoting drugs resistance or hospital acquired infections, or use them only as a last resort.
7)Drain the infected foci quickly and remove all potentially infected devices.
8)Always try to de-escalate antibiotic treatment according to clinical situation and microbiological results.
9)Stop unnecessarily prescribed antibiotics once the absence of infection is likely.
10)Don’t work alone
Setup local teams with infectious diseases specialist,clinical microbiologist,hospital pharmacist, infection control practitioner and comply with hospital antibiotic policies and guidelines.
By : Marwa Elsayed .
Drug information Specialist PGCPD, Bsc .
Drug and Poison information Center .
References : Int J Antimicrobial Agents 2016 Sept ; 48(3) 239-46 ,doi:10.1016/j.ijantimicag.2016.06.015. Epub 2016 july 25.